CORRELATION OF ROUTINE HEMATOLOGY RESULTS AND RMT RESULTS OF CEPHEID XPERT® XPRESS SARS-CoV-2 WITH SEVERITY IN COVID-19 PATIENTS AT MERAUKE HOSPITAL

Abstract

The degree of severity is an important consideration in COVID-19 patients. The correlation of routine hematology results and rapid molecular test (RMT) Cepheid Xpert® Xpress SARS-CoV-2 results has not been much researched, even though many laboratory tests have been carried out, but not many result were related to the degree of severity. Therefore, the present study is aimed at determining the correlation of routine hematology results and RMT  CepheidXpert® Xpress SARS-CoV-2 results with the degree of severity in COVID-19 patients at Merauke Hospital.This was  a retrospective cohort study, at the Laboratory of Clinical Pathology and Medical Records In patients and Out patients at Merauke Hospital, between November-December 2020, routine hematology examinations and RMT Xpert® Xpress SARS-CoV-2 in COVID-19 patients at D0 and D7 wide examinated.The number of research samples was 116. There was no relationship between RMT D7 and severity, positive and negative RMT were found in the majority of mild severity. The results of routine hematology D0 and D7 were not much different, except for WBC. There was no significant correlation between Ct gene E (D0, D7), Ct gene N2 (D7) with the degree of severity. Monocytes, MLR, PLR, PLT D0 correlated with the severity. RMT results did not correlate with severity. There was no significant correlation between Ct gene N2 and D0 severity. Statistical data were performed using the Pearson, Spearman, SPSS 32 correlation test. It is suggested to perform a further research using different research designs, detecting all target genes and other laboratory parameters.