TREATMENT PROFILE AND CLINICAL OUTCOMES OF COVID-19 PATIENT WITH DIABETES MELLITUS IN INDRAPURA FIELD HOSPITAL INDONESIA

Erwin Astha Triyono, Joni Wahyuhadi, Jongky Hendro Prajitno, Hermina Novida, Nenci Siagian, Cupuwatie Cahyani, Arinditia Triasti Putri, Karisma Septari Idamusaga, Nastiti Imana Intansari, Jose Asmara, Agrasenfani Hadi, I Ketut Mega Purnayasa Bandem

Abstract


Diabetes mellitus is one of the leading causes morbidity and mortality in adult with COVID-19 worldwide and definitive treatment has not yet been established. To describe treatment and clinical outcomes of COVID-19 patient with Diabetes mellitus. In this descriptive study, we reviewed the electronic medical records of patients at Indrapura Field Hospital, Surabaya, Indonesia from May 2020 to February 2021. A total of 260 patients who had confirmed COVID-19 with Diabetes Mellitus were included. Demographic data, laboratory data, therapy, and clinical outcomes were collected and analyzed. This study showed that 140 patients were males (53.8%) and the mean age was 51 years old. Hypertension was the main comorbid disease (47,7%), followed by obesity class I (38,1%). Cough (47.7%) and fever (23.8%) were most common clinical symptoms. Based on medical history, 189 (72.7%) patients had uncontrolled diabetes mellitus and some of them came with moderate and severe COVID-19 (5,8% and 10,5%). Anti-viral agent was not prescribed in this centre. During admission all patients received vitamin. Symptomatic treatment was given to some patients such as oxygen (11.9%), antitussive (47.3%), and antipyretic (24.7%). Regarding the treatment of diabetes mellitus, 150 patients (57,6%) received oral antihyperglycemia, 75 patients (28.8%) received insulin, and 22 patients (8.4%) received both. The average fasting blood glucose level on admission improved before discharged (210.75mg/dL vs182.03 mg/dL) and similarly the average 2-hour postprandial blood glucose level (271,19 mg/dL vs 222,01 mg/dL). There were 202 patients (77.7%) stayed in the hospital more than 10 days. At the end of treatment, 229 patients (88.1%) were confirmed to had recovered from COVID-19, 29 patients (11.2%) were referred for desaturation. No patient died during treatment. Symptom management, supportive treatment, and antihyperglycemia drugs were given during hospitalization and most of patients recovered form COVID-19 after treatment.


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